4-Benzyloxy-2-methylphenylboronic acid, identified by CAS 847560-49-0, is an aromatic boronic acid used primarily as a research and synthetic building block. Its structure combines a boronic acid group with a methyl substituent and a benzyloxy-protected phenoxy functionality, giving chemists several points for controlled molecular transformation. I recommend evaluating this material through its identity, structure, intended reaction, documentation, and supply requirements rather than relying only on a product name.
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Based on the stated structure, the compound is commonly represented by the molecular formula C14H15BO3 and a calculated molecular weight of approximately 242.08 g/mol. The CAS number is 847560-49-0, which should be cross-checked against the supplier’s certificate of analysis and product specification before procurement. Maison Chemical supports qualified B2B buyers with product information, quotation discussions, documentation review, and supply coordination for this type of organic boronic acid.
4-Benzyloxy-2-methylphenylboronic acid contains an aryl boronic acid moiety, written generally as Ar–B(OH)2. The boronic acid group is the principal reactive handle and can participate in carbon–carbon bond-forming chemistry, especially palladium-catalyzed cross-coupling such as Suzuki–Miyaura reactions. The benzyloxy group is an ether functionality that may serve as a protected or differentiated oxygen-containing substituent in a multistep synthesis.
The methyl group modifies the electronic and steric environment of the aromatic ring. In practical synthesis planning, this substitution pattern can influence reaction behavior, purification, solubility, and the properties of the final coupled product. These effects are project-dependent, so I advise buyers to confirm performance in their own reaction system rather than treating the compound as interchangeable with every other arylboronic acid.
| Property | Information |
|---|---|
| Product name | 4-Benzyloxy-2-methylphenylboronic acid |
| CAS number | 847560-49-0 |
| Estimated molecular formula | C14H15BO3 |
| Calculated molecular weight | Approximately 242.08 g/mol |
| Main functional groups | Aryl boronic acid, aromatic ether, methyl-substituted benzene ring |
The most important function of this compound is its use as an arylboronic acid building block. In an appropriate reaction system, the boronic acid group can be coupled with an aryl or vinyl halide to create a new carbon–carbon bond. This makes the material relevant to medicinal chemistry, process research, agrochemical discovery, and broader small-molecule development.
The benzyloxy substituent provides an additional structural feature that can be retained in the target molecule or modified in a later step. Depending on the synthetic route, chemists may use hydrogenolysis or another validated deprotection strategy to convert a benzyloxy group into a phenolic function. The suitability of any deprotection method depends on the complete molecular structure and the stability of other functional groups present.
These are potential research and synthetic uses, not a guarantee of performance in a specific application. Reaction yield, selectivity, stability, and purification behavior depend on catalyst choice, solvent, base, temperature, concentration, substrate compatibility, and the quality of the starting material. Buyers should therefore assess the compound against a defined experimental or process specification.
At discovery scale, the key requirement is usually reliable identity and sufficient material for parallel reaction screening. A buyer may prioritize a clear product description, batch-specific analytical data, suitable packaging, and rapid communication about availability. Small quantities can be useful when the compound is being evaluated as one member of a broader building-block library.
For process development, the purchasing decision becomes more detailed. The project team may need consistent batch quality, controlled moisture exposure, repeatable packaging, and documentation that supports internal quality procedures. Before increasing order volume, I recommend confirming the applicable specification, retest or shelf-life information, storage recommendation, and whether a representative sample can be reviewed.
Material options can differ by quantity, packaging format, analytical documentation, and commercial terms. Not every supplier offers the same batch size or customization pathway, so buyers should ask directly about available quantities instead of assuming that a catalog listing represents unlimited stock. Maison Chemical can discuss standard supply and project-specific requirements according to the buyer’s target quantity, destination, documentation needs, and timeline.
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At minimum, I suggest confirming the product name, CAS number, molecular formula, molecular weight, appearance, assay or purity method, and batch identification. Depending on the application, buyers may also request chromatographic data, NMR information, water content, residual solvent data, or other tests included in the supplier’s standard certificate of analysis. The exact specification should be agreed before purchase, particularly when the material will enter a regulated or quality-controlled workflow.
Physical properties such as melting point, solubility, and long-term stability should not be assumed without batch-specific or validated reference data. Boronic acids can show sensitivity to moisture, temperature, concentration, and chemical environment, while laboratory behavior may vary with solvent and formulation. A supplier’s safety data sheet should be reviewed before handling, storage, transport, or disposal.
The container should protect the material from contamination and, where appropriate, excess moisture. The correct storage condition must follow the supplier’s SDS and product-specific recommendations rather than a generic rule for all boronic acids. Receiving teams should inspect the package, label, lot number, and visible condition promptly and report discrepancies before the material is introduced into a synthesis.
A suitable supplier should be able to identify the material unambiguously and explain which analytical documents accompany the shipment. I recommend asking whether the quoted material corresponds specifically to CAS 847560-49-0 and whether the supplier can provide a batch-linked certificate of analysis. If your project has a defined impurity, moisture, or residual-solvent limit, communicate that requirement before quotation.
Price alone does not determine the total sourcing cost. Buyers should compare minimum order quantity, packaging, lead time, shipping terms, export documentation, payment terms, and the cost of qualification or resampling. For international orders, it is also sensible to confirm the destination-country requirements and whether the supplier can prepare the documents required by the importer or internal purchasing department.
Maison Chemical approaches this product as a B2B sourcing requirement rather than only a catalog transaction. We can help buyers clarify the required quantity, intended research stage, documentation package, destination, and delivery expectations before a quotation is finalized. This approach helps distinguish a discovery-scale request from a process-development requirement.
For qualified inquiries, we can discuss product identity, available supply options, packaging, certificate of analysis requirements, SDS documentation, and potential repeat-order planning. Where a project has special quality or logistics conditions, the most efficient process is to provide those conditions at the beginning so that the proposed supply route can be reviewed accurately. Availability, specifications, and lead time should be confirmed for each order because they may vary by batch and project.
4-Benzyloxy-2-methylphenylboronic acid CAS 847560-49-0 is a specialized aromatic building block for synthetic research where its aryl boronic acid, benzyloxy, and methyl-substituted structure are relevant. It may be a suitable choice for cross-coupling studies, medicinal chemistry programs, and route-development work, provided that its identity and batch quality match the project specification. It should not be selected solely because it belongs to the broad category of organic boronic acids.
The practical next step is to prepare a clear inquiry containing the required quantity, target purity or analytical specification, packaging preference, destination, documentation needs, and requested delivery window. Send these details to Maison Chemical for a product and supply discussion. We can then review the appropriate sourcing option and help you determine whether this compound fits your research or commercial development workflow.
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